Our News

Cancer: 'Tumour monorail' can lead cancers to their doom

Cancer "monorails" can be used to kill tumours by luring them into toxic pits or areas of the body that are safer to operate on, say US researchers.

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Promising brain tumor treatment hijacks "monorail" that lets cancer spread

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Lessons learned from phase 3 trial of immunotherapy for GBM (2024)

Glioblastoma (GBM)'s median overall survival is almost 21 months. Six phase 3 immunotherapy clinical trials have recently been published, yet 5/6 did not meet approval by regulatory bodies. For the sixth, approval is uncertain.

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Unlocking the power of investigative biopsies in glioma (2025)

Glioblastoma (GBM) is a primary brain cancer with a devastating prognosis with limited treatment options. Stereotactic biopsies are performed routinely for histological and molecular diagnosis, but could they also be performed for detailed multi-omics investigation into the tumor microenvironment?

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Device-assisted strategies for drug delivery across the blood-brain barrier to treat glioblastoma (2025)

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Enroll in the trial

Exvade is conducting a First-in-Human study of the Tumor Monorail Device at the Preston Robert Tisch Brain Tumor Center at Duke University, evaluating its safety and advancing a transformative shift in how cancer is treated.

Enroll in our clinical trial and contribute to the development of innovative solutions that prioritize patient care and outcomes.

“By allowing real-time monitoring of the tumor over time, while on therapy, we will hopefully be able to more swiftly identify the degree of efficacy or the limitations of our therapies, while preventing the trauma and costs of repeated brain surgery.”

- Dr. Annick Desjardins, MD, FRCPC, neuro-oncologist,
professor of neurosurgery and neurology at Duke University